Phthalimide-PEG4-MPDM-OH 0-hydroxyecdysone In MX-1 xenograft tumor model

In MX-1 xenograft tumor model studies

Smiles: CC(C)(C)C1=CC(=CC(=C1OCCCC(=O)NCCCN1C=C(CN(CC(N)=O)C(=O)CN(CCC)C(=O)CN(CCC)C(=O)CCCOC2C=C(C=CC=2)C2NC3=CC(=CC=C3N=2)C2NC3=CC(=CC=C3N=2)N2CCN(C)CC2)N=N1)C(C)(C)C)C1NC2=CC(=CC=C2N=1)N1CCN(C)CC1

16S)-8-hydroxy-5'

NC1C=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)C(=O)N=1

3-b]indol-1-one

Phthalimide-PEG4-MPDM-OH 0-hydroxyecdysone In MX-1 xenograft tumor modelPhthalimide PEG4 MPDM OH is a PROTAC linker, which refers to the PEGs composition. Phthalimide PEG4 MPDM OH can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin proteasome system to selectively degrade target proteins. Product information Molecular Weight: 436. 50